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.. VIII ...

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Candida.

. 298 Candida 283 . .. 2003 .

2004 . ATB-Expression (BioMerieux, France). , () , M44-P NCCLS (National Committee for Clinical Laboratory Standards) BIOMIC System (Giles Scientific Inc.). (), . 282 , (breakpoint), . NCCLS breakpoint. 2003 . NCCLS , - .. 8 /;

- 16 32 /, ( ) 64 / : 19 , 15 18 14 . , 25 (Pfizer, Inc.) 1 (Pfizer, Inc). 7 Candida albicans ATCC 90028 ( 2839 3142 ) Candida parapsilosis ATCC 22019 ( 2833 2837 ). Breakpoint

. 13 .

. 20 . (32,6%) (22,5%). 16 . :

1. C. albicans 58,4% 2. C. glabrata 11,1% 3. C. parapsilosis 8,7% 4. C. krusei C. sake 5,4% 4,7% 5. C. tropicalis C. inconspicua 2,3% , .

, 8% (22/283) . 6,4% (19/298) . C. albicans (52,6%). C. sake, , , , . non-albicans Candida 47,4% (9/19), , C. parapsilosis (31,6%). C. parapsilosis (65,4%), - .

C. glabrata, , (30,3%).

33,6% (100/298) , 3% (9/298) - . , C. albicans C. glabrata, 29,9% (52/174) 27,3% (9/33). C. krusei (81,3%, 13/16) C. parapsilosis (61,5%, 16/26). in vitro, 20,5% (61/298) , 4 16: C. tropicalis (42,9%, 3/7), C. albicans (28,7%, 50/174), C. glabrata (15,2%, 5/33) C. krusei (18,8%, 3/16). . , C. parapsilosis (100% 26,9% , p0,0001), C. sake (100% 71,4% , p0,05), C. inconspicua (100% 286% , p0,05), C. krusei (81,3% 12,5% , p0,0001). , C. tropicalis ( 57,1% ). C. albicans (70,1% 71,3% ) C. glabrata (84,8% 69,7% ). 100 39. 52 C. albicans, , 2 (3,8%). 9 C. glabrata, , 4 (44,4%) . , in vitro , C. parapsilosis ( 16 , , ), C. krusei (76,9%, 10/13), C. inconspicua (100%, 3/3), C. sake (100%, 3/3), , .

, . ( 2003 . 2004 .), C. albicans (50,7%, 34/67), C. glabrata (14,9%, 10/67) C. krusei (11,9%, 8/67), C. inconspicua (7,5%, 5/67). (20002002 .) Candida, 284 . (20002002 ) ( 2003 2004 ) Candida, . , albicans ( non albicans Candida). , 2000 . non-albicans Candida 22,7% (15/66), 2001 . 29,3% (94/321), 2002 . 29,9% (52/174) non-albicans Candida 49,3% (33/67), , 2002 .

(p0,05). (2000-2002 .) C. albicans 71,3% (400/561) , ( 2003 2004 .) C. albicans 50,7% (p0,002). C. tropicalis (17/561, 11,9% 2/67, 29%, p0,001). , C. krusei (11/561, 1,9 8/67, 11,9, p0,02). . .

2004 . Candida, , , . , C. albicans, 96,5% 50% (386/400 17/34 , p0,0001), C. krusei, 63,6% 0% (7/11 0/8 , p0,0001), C. tropicalis, 88,2% 0% (15/17 0/2 p0,0001).

C. glabrata C. inconspicua : 87,3% (48/55) 70% (7/10), 86,8% (33/38) 40% (2/5) . , C. parapsilosis C. kefyr, 100% . in vitro

(20,5% 33,6% , p0,001), , (24/67, 35,8%) (32/67, 47,8%) . , C. albicans C. tropicalis, , . 3 C. glabrata, , 1 (33,3%). 8 C. krusei, , 5 (62,5%). , C. inconspicua, , .

, , . , . , non-albicans Candida.

.., ..

- , . . . , . . , .

, , . , . (1031 ), 86 . , 22% . , , 286 , .

, , . Streptomyces sp., , , 12 , 9 , 9 . . - , . .

VIII. A .. 251, 263 .. 7, 17, 161, 229, .. 49 - .. .. 155 .. 42, 161, .. 14 .. . 29 .

. .. 138 .. .. 154 .. .. 151 .. .. 100 .. .. 63 .. .. 70 .. .. 140 .. .. 141 .. .. 98, .. .. 71 .. .. 155 .. .. 155 .. 43, .. 132 .. .. 250 .. .. 254, .. 25, 82, .. 24 .. .. 156 .. .. 250 .. .. 251, 263 .. .. 168 .. 121, .. 127 .. 168, .. 11 .. .. 50 .. .. 156 .. .. 234, 270 .. .. 19 .. 98, .. 57 .. .. 132, .. 4, 5, 94, 96, 105, 159, 203, 224 .. .. 4, 5, 159 .. .. 100, 179, 180, 181 .. .. 127 .. .. 82 .. .. 110 .. .. 53, 55 . .. 112, 113, 116, 276 .. .. 161 .. 288 .. 238 .. 19 .. 5, 83, .. 169 .. .. 203, 224 .. 145, .. 254, 255, 256 .. 26, .. .. .. 118, 121, .. .. .. .. 210, .. 123, .. .. 38, 87, .. .. .. .. .. .. .. .. 171, .. 30, .. 98, .. .. 46, .. .. .. .. .. .. .. 171, .. .. .. .. .. .. .. 220, 222, .. .. 29, .. .. .. .. .. .. .. 38, 105, .. .. .. .. .. .. .. .. 106, .. 112, .. .. .. 11, .. .. .. .. 30, 144 .. . .. .. 4, .. .. .. 176, .. .. . .. 7, 229, VIII. .. 185 .. 79 .. .. 80 .. .. 98, 103 .. .. 4, 5, 105, 159, 203, 224 .. 180, .. 159 .. .. 100 .. .. 98, 103 .. .. 25 .. .. 166 .. .. 60 .. .. 232 . .. 100, 179, 180, 181 .. .. .. .. 279 .. 182, 192, 194, .. 80 .. .., 192 .. 31, .. 20, 239, 243, 245 .. .. 148, 150 .. .. 87, .. 279 .. 271, 273 .. .. 182, 192, 194, 196 .. .. 106 .. 17, 161, .. 127 .. 182, 192, 194, .. 203, 224 .. 199, .. 185 .. 199, .. 82 .. .. 52 .. .. 185 . .. 16 .. .. 132 .. .. 37, 120 .. .. 35, 118 .. 100, 179, 180, .. 35 .. .. 145, 187, 189 . 254, . 101 .. .. 168 .. 53, . 38, 64 .. 251, .. 105, 239, 243, 245 .. .. 55 .. .. 188, 261 .. .. 250 .. .. 127 .. .. 168, 290 .. .. .. .. .. 83, .. 205, 206, .. .. .. .. .. .. .. .. .. .. .. .. .. 30, .. .. .. .. .. .. .. .. 98, .. 210, .. .. .. .. .. 83, .. .. .. .. .. 118, .. .. 38, 105, .. .. 98, .. .. .. 53, .. 196, .. 25, .. .. .. .. .. .. .. .. 43, .. 57, .. 76, 220, 222, .. .. .. 20, 38, 64, 87, 89, 91, .. 94, 96, 105, 239, 241, 243, 245, .. .. . .. 38, 64, 87, 89, 91, 94, .. 96, 105, 239, .. 76, 220, 222, .. .. .. .. .. 203, .. 7, 17, .. .. 7, 17, 161, 229, .. .. 7, 17, .. .. .. VIII. .. 53, 55 B .. 132 Bachnio S. D .. Dbkowska M. J .. Jaworska-Zaremba M. .. 171, .. 38, .. uczak M. S .. 266, .. 145, 187, 189 Stelmach E. .. 57, 63 Swoboda-Kope E. .. .. .. .. .. .. 38, 94, 96, .. .. 234, .. 19, 235, 236, .. .. 121, 292 :

.., .., .., ..................................... .., .., .., .., .., .., .............................................. .., .., .., .., ............................................................................................................ ............................................................................................................ - - 20002004 .

.., .., .., ......................... 20032004 ............................................................................................................ .., .................................................................................. .., .., ................................................... .., ................................................................................... .., .., ............................................................ .., ....................

............................................................. ( ) 10 .., .., .., .., ........................................................................................................... , 8 . 2003 2005 .., ...................................................................................... .., .., .., ............................ :

.., ...................................................................................... Candida .., ..................................................................................... .., .., .., .., ........................................................................................................ , .., .., .., ....................... Candlda albicans - .., ......................................................................... .., .., ....................................................... Candida .., .., ............................................................. - .., .., ............................................................ 294 Penicillium LINK Aspergillus LINK ., ............................................................................ .., .., ................................................... Candida spp. .., .., .., ..................... .., .., .., .., .., .., .., .., ........... . ........................................................................................................... - .., .................................................................................... - ?

.., ., ..................................................................... .., ........................................................................... I Candlda albicans .., .., .................................................. .., .., .................................................... ......................................................................................................... Trichophyton, Penicillium, ANDIDA 2 , .., .., ........................................................ .., ................................................................................... Candida IL- In vitro .., .., .., ..................... Candlda albicans .., .., .., .., .., ............................................................................ NRAMP1 .., ., ., ............................ .., .., .., .., .., ................................................................................. .., .., .., ..................... .., .., ............................................................. EVALUATION OF ENZYMATIC ACTIVITY OF Candlda albicans ISOLATED FROM CLINICAL SPECIMENS OF A KIDNEY TRANSPLANT RECIPIENT Swoboda-Kope E., Dbkowska M., Bachnio S., Stelmach E., Jaworska-Zaremba M., uczak M............................................................................ .., ................................................................................. Malassezia furfur .., .................................................................................... - .., ...................................................................................... 296 , .., .., ................................................... CANDLDA ALBICANS .., .., ....................................................... ........................................................................................................... G, , .., .., .., .......................... CANDLDA ALBICANS SCREEN-PRINTED .., .., .., .., .......... .., .., .................................................... K .............................................................................................................. ߻ ?

.., .., .., .................................. .., .., .., .................................. - .., ..................................................................................... . I: .., .., .., ........................................... . II: .., .., .., ........................................... COCCIDIOIDES IMMITIS COCCIDIOIDES POSADASII .., .., .., .., .., .., ........................................................ - .., .., .., .., .., .., ......................................... .., .., ..................................................... .., .., .., .., .., .., .................................................. - .., .., .., .., .., .., .., .., .............................. ITS , A.VERSICOLOR .., .., .., .., ...... : , ................................................................................................... .., ................................................................................. ............................................................................................................. ............................................................................................................ .., .., .., .., .......................................................................................................... 298 . .., ........................................................................... .., .., .., .., .., .., .., .., .., .......................................................................................................... ............................................................................................................. .............................................................................................................. .., .., .., .., .., .., .., ............................ - .., ..................................................................................... .., .., .., .., .., .., .., .., .., ..,. .., .., .., .., .., .., ................................................................................ - () .., .., .................................


.................... .., ................................................................................. .., .., ................................................................... .., .., .......................................... .., .., .., .., .., ............................................................................... ......................................................................................................... .., .., .................................................... Candida .., .., ........................................................... .., .., .................................................. - ............................................................................................................. , , .., ...................................................................... .., .., .................................................. .., .., ........................................................ , , MALASSEZIA .., - .............................................................. 300 .., .., ............................................................ .., .., ...................................................... .., .., .., .., .., .., .., .., .., ............................................................................. .., ................................................................................. .., .., .., .., ......................................................................................................... ......................................................................................................... һ ........................................................................................................ » .., .., .., ................................. - .., .., .., .., ....................................................................................................... .., ................................................................................... .., .., .., ................................... - .., .., .., .................................. ............................................................................................................. - .............................................................................................................. .., .., .., .., ........................................................................................................... .., ................................................................................. ?


.., .., .................................................... ?

.., .., .., .................... - .., .., .., .................... .., .., ......................................................... .., .., .., .., .., .................................................................................. .., .............................................................................. .., .., ..................................................... .

.., .., .., .., ........................................................................................................ , .., .., .., .., .............................................................................................................. .., .., ........................................................ .., .., .., ................................... .., .., .., ................................ 302 ( ) .., .......................................................................... .., .............................................................................. .., .., .., .., ........................................................................................................ .., .., ................................................... ........................................................................................................ .., ......................................................................... .., .., ...................................................... .., ..................................................................... .., ..................................................................... , .., ................................................................................... , , .......................................................................................................... .., .., ........................................... .., .., ........................................... II .., .., ........................................... .., .., .., .., ........................................................................................................ .., .., .., ......................... .......................................................................................................... - .., .., .., .., ..................................................................................................... - () .., .., .., .., .......................................................................................................... .

., .., .......................................................... .., .., .................................................... .., .., ......................................................... ......................................................................................................... .., .., ........................................... : 7 .., .., .., .., .., .., ......................................................... : ........................................................................................................... .., .., ............................................................. :

.., .., .., .., .., ............................................................................... 304 : .., .., ....................................................... һ

.., .., ............................................... .., .................................................................................... .................................................................................................. .., .., ............................................................. .., .., .............................................................. .., .., ................................................................ .............................................................................................................. ............................................................................................................. .., ............................................................................... () .., .., ..................................................... .., ............................................................................. .., .., .............................................. .., .................................................................................. () .., ................................................................................. .., ................................................................................... .., .., ............................................................... .., .., .., ....................... ..................................................................................................... ............................................................................................................. , .., , ......................... () - .., .., .., .............................. , : .., ............................................................................ .., ............................................................................... .. VIII

http://www.mycology.ru 28.02.2006 . 6090/16.

. . . 19,25. 900

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