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1. Biological effects of shock waves: kidney haemorrhage by shock waves in doge administration rate dependence / M. Delius, M. Jordan, H. Eizenhoefer [et al.] // Ultrasound Med. Biol. - 1988. - Vol. 14. - P. 689-694.

2. Clinical predictors of stone fragmentation using slow-rate shock wave lithotripsy / W.M. Li, W.J. Wu, Y.H. Chou [et al.] // Urol. Int. 2007. Vol. 79, 2.

P. 124-128.

3. Cumulative renal damage in dogs by repeated treatment with extracorporeal shock waves / H. Koga, K. Matsuoka, S. Noda [et al.] // Int. J. Urol. - 1996. - Vol. 3, 2. - . 134-140.

4. Extracorporeal shock wave lithotripsy at 60 shock waves/ min reduces renal injury in a porcine model / B.A. Connors, A.P. Evan, P.M. Blomgren [et al.] // B.J.U.

Int. 2009. Vol. 104, 7. P. 1004-1008.

5. Guidelines on Urolithiasis / C. Turk, T. Knoll, A. Petrik [et al.] // European Association of Urology. - 2012. - P. 29-30.

6. Optimal frequency in extracorporeal shock wave lithotripsy: prospective randomized study / . Yilmaz, . Batislam, . Basar [et al.] // Urology. 2005. 6. P. 1160-1164.

7. Shock wave lithotripsy at 60 or 120 shocks per minute: a randomized, double blind trial. Pace KT, D. Ghiculete, M. Harju [et al.] // J. Urol. 2005. Vol. 174, 2.

P. 595-599.

8. Slow versus fast shock wave lithotripsy rate for urolithiasis: a prospective randomized study / K. Madbouly, A.M. El-Tiraifi, M. Seida [et al.] // J. Urol. 2005.

Vol. 173, 1. P. 127-130.

9. The effect of shock wave rate on the outcome of shock wave lithotripsy: a meta-analysis / M.J. Semins, B.J. Trock, B.R. Matlaga // J. Urol. 2008. Vol. 179, 1. P. 194-197.

128 ISSNͲߠίȠ.2013.80..1..1 10. Why stones break better at slow shockwave rates than at fast rates: in vitro study with a research electrohydraulic lithotripter / Y.A. Pishchalnikov, J.A.

McAteer, J.C. Williams [et al.] // J. Endourol. 2006. Vol. 20, 8. P. 537-541.

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A.A.Lyulko, A.V.Stets, A.O. Burnaz, I.N.Nikityuk, A.S.Sagan State Institution "Zaporozhye Medical Academy of Postgraduate Education Ministry of Health of Ukraine " COMPARATIVE EFFICACY AND SAFETY OF LITHOTRIPSY WITH VARYING FREQUENCY SHOCK WAVE GENERATION The results of the study, the purpose of which was to increase the efficiency and safety of extracorporeal lithotripsy by selecting the optimum pulse frequency of the shock wave. The study included 125 patients having upper urinary tract calculi in size from 8 to 20 mm. The study included patients with preserved renal function without evidence of active pyelonephritis and ureterohydronephrosis.

To assess the degree of tissue damage to the shock wave lithotripsy and the next day in the urine were determined after 3 bio-chemical markers: gidroksiguanozin being the most revealing marker of damage to nucleic acids in various pathological conditions, and two pochechnospetsificheskih enzyme - glyutationaminotransferaza and acetylglucosaminidase.

It is established that the conduct of extracorporeal lithotripsy stones localized in the kidney is the most optimal frequency shock waves - 100 pulses per minute.

Image pulse frequency leads to a more pronounced Nome renal tissue damage.

Reducing the pulse frequency according inexpedient, as it does not lead to a significant reduction of injury tion buds, but slightly reduced the effectiveness of the destruction of the stone and extends lithotripsy session.

When the stones are located in the urine source by appropriate holding lithotripsy shock wave with a frequency - 150 ppm as the frequency of pulses at a given location without significant effect on the growth of tissue trauma at the same time, increasing the pulse frequency increases the efficiency of destruction concretions.

Keywords: ESWL, the pulse of the shock wave, the effectiveness of destruction of the stone, damaged kidney tissue.

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ISSNͲߠίȠ.2013.80..1..1 1. .., . . - .: , 2001. - . 42-51.

2. .., .. - 㳿: 3- . 2- ., . . : -VAL, 2001. 519 . . 3.

3. Akcetin Z., Zugor ., Elsasser D. Does the distance to normal renal parenchyma (DTNRP) in nephron-sparing surgery for renal cell carcinoma have an effect on survival? // Anticancer Res. - 2005. - Vol.25,N3A. - .629-632.

4. Hafez K.S, Fergany A.F., Novick A.C. Nephron sparing surgery for localized renal cell carcinoma: impact of tumor size on patient survival, tumor recurrence and TNM staging //J. Urol. - 1999. - Vol.162, N6. - P.1930-1933.

5. Jescbke K., Peschel R., Wakonig L. et al. Laparoscopic nephron-sparing surgery for renal tumors // Urology. - 2001. - Vol. 58. - P. 688-692.

6. Leibovich B.C, Blute M.I., Cheville J.C. Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy //J. Urol. - 2004. - Vol.171, N3. - P.1066-1070.

7. Li Q.L., Guan H.W., Zhang Q.P. Optimal margin in nephron-sparing surgery for renal cell carcinoma 4 cm or less // Europ. Urol. - 2003. - Vol.44, N4. - P.448 451.

8. Meng M.V., Freise .E., Stoller M.L. Laparoscopic nephrectomy, ex vivo excision and autotransplantation for complex renal tumors //J. Urol. - 2004. Vol.172, N2. - .461-464.

9. Patard J.J., Shvarts O., Lam J.S. Safety and efficacy of partial nephrectomy for all T1 tumors based on an international multicenter experience //J. Urol.- 2004. Vol.171(6 Pt 1). - P.2181-2185, quiz 2435.

10. Piper N.Y., Bisboff J.T., Magee C. Is a 1-CM margin necessary during nephron-sparing surgery for renal cell carcinoma? // Urology. - 2001. - Vol.58, N6. P.849-852.

11. Ramani A.P., Desai M.M., Steinberg A.P. Complications of laparoscopic partial nephrectomy in 200 cases //J. Urol. - 2005. - Vol.173, N1.-P.42-47.

12. Rasweiler J., Abbou C., Janetschek G. et al. Laparoscopic partial nephrectomy, the European experience // Urol. Clin. N. Amer. - 2000. - Vol. 27. - P. 721-736.

13. Thompson R.H., Leibovich B.C., Lohse C.M. Complications of contemporary open nephron,sparing surgery: a single institution experience //J. Urol. - 2005. Vol.174, N3. - P.855-858.

: 19.03. .., .., .., .. ϲͲ вײ ˲ 136 ISSNͲߠίȠ.2013.80..1..1 19 䳿 1-2 NoMo . , 1-2 NoMo , . , , . - .

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O.O.Lyulko, O.O.Burnaz, O.S.Sagan, I.M.Nikituk State Institution "Zaporozhye Medical Academy of Postgraduate Education Ministry of Health of Ukraine " LAPAROSCOPIC PRESERVING TREATMENTS KIDNEY CANCER The results of treatment of 19 patients with renal cancer in stage T1-2 NoMo made after sparing retroperitoneal laparoscopic partial nephrectomy and transperitoneal access.

Analysis of the results showed that laparoscopic resection of the kidney for renal cell cancer T1-2 NoMo achieves bezretsi-wondrous period of time without conceding open resection for transkostalnyh or subkostalnyh access. The method chosen by laparoscopic approach depends on the size, location of the tumor and the anatomical features of the operated area. Minimally invasive laparoscopic approach reduces postoperative hospital day and improve the quality of life of the patient in the early postoperative period with disease-free survival.

For laparoscopic access method definition, location and size of the tumors is of great importance, transperitoneal access often used for tumor localization in the upper and middle segments of the anterior surface of the kidney.

In this visualization of the tumor and renal pedicle carries out without technical difficulties.

In other instances, the retroperitoneal approach. With the right criteria for assessing the localization of the tumor, its volume performed in this area before surgery, the presence of a complete technical equipment and laparoscopic experience of the operating surgeon, you can avoid almost all the possible complications of this treatment.

Key words: laparoscopy, kidney cancer, retroperitoneal, transperitoneal.

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1.Posner G., Krotoszyner M. Diagnosis and treatment of chronic prostatitis are worthy of notice // Int. Or. Url.-1893.-P. 2. .., .., .. : ..-., 1980.

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7. Bennet B.D., Richardson P.H., Gardner W.A. Histopatology and cytology of prostatitis // Prostate diseases / Eds. H. Lepor, R.K. Lawson. Phadelphia: 1993. P.

399 413.

8. Histopatology of prostatitis / B.D. Bennet, D.E. Culberson, C.S. Petty et al. // Urology. 1990. Vol. 143. P. 265.


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O.O.Lyulko, O.O.Burnaz, I.M.Nikituk, O.S.Sagan, N.A.Gorbaty State Institution "Zaporozhye Medical Academy of Postgraduate Education Ministry of Health of Ukraine " DEFINING THE CRITERIA OF RISK OF RELAPSE OF CHRONIC ABACTERIAL PROSTATITIS CLINICAL AND BIOCHEMICAL PARAMETERS IN THE SECRET OF CANCER The analysis of the long-term results of treatment and 560 patients who were treated at the hospital and outpatient care. After the analysis of 560 case histories of patients determined that 150 of these relapses occurred more than 1 time per year, and they were included in the study course after appropriate examination.

The purpose the study was to determine the correlation between the intensity of pain, of dysuric and other clinical manifestations of the frequency of relapses in patients with chronic prostatitis in assessing the performance of cytokine IL-1 and sIgA, as potential markers of recurrence of chronic prostatitis.

Relapses and disease duration is inversely correlated with the level of immunoglobulin (an indicator of local immunity). The higher levels of immunoglobulin A, the lower the risk of recurrence. The recurrence rate is not dependent on clinical signs and duration of disease. Having a patient with chronic prostatitis sIgA values below this value will require additional monitoring and prophylactic treatment to prevent relapse of disease and complications.

The duration of treatment and rehabilitation is based on the level of secretory IgA indices and cytokine IL-1b in prostatic secretions.

In the presence of elevated levels of proinflammatory cytokines IL-pancreatic secretion-1 (more than 480pg/ml) in combination with low level of secretory IgA 148 ISSNͲߠίȠ.2013.80..1..1 (less than 50 ug / ml) are highly significantly (more than 3 times a year) relapse rate (probability of more than 95% ).

Key words: abacterial prostatitis chronic, recurrent chronic prostatitis, prostatic secretions, interleukins, secretory immunoglobulin A, the risk of relapse of chronic prostatitis, the local immunity.

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1. Vogler J.B., Murphy W.A. Bone marrow imaging / Radiology. 1988. - V.168. P. 679-693.

2. Vande Berg B.C., Malghem J., Lecouvet FE, et al. Magnetic resonance imaging of the normal bone marrow / Skeletal. Radiol. 1998. V. -,27. P. :471 483.

3. Porter B.A., Shields A.F., Olson D.O. Magnetic resonance imaging of bone marrow disorders / Radiol.Clin. North. Am. -1986. V.24. P. 269-289.

4. Mitchell D.G., Rao V.M., Dalinka M. et al. Hematopoietic and fatty bone marrow distribution in the normal and ischemic hip: new observations with 1.5-T MR imaging / Radiology. -1986. V. 161. P. 199-202.

5. Stabler A., Doma A.B., Baur A. et al. Reactive bone marrow changes in infectious spondylitis: quantitative assessment with MR imaging /. Radiology.- 2000. V.217. P. 863868.

6. Bordalo-Rodrigues M., Galant C., Lonneux M. et al. Focal nodular hyperplasia of the hematopoietic marrow simulating vertebral metastasis on FDG positron emission tomography / AJR. 2003. V.180. P. 669671.

7. Poulton T.B., Murphy W.D., Duerk J.L. et al. Bone marrow reconversion in adults who are smokers: MR imaging findings /AJR.- 1993. V.161. P. 1217 1221.

152 ISSNͲߠίȠ.2013.80..1..1 8. Ricci C., Cova M., Kang Y.S., Yang A. et al. Normal age-related patterns of cellular and fatty bone marrow distribution in the axial skeleton: MR Imaging Study1/ Radiology.-1990.- V. 177. P.83-87.

9. Poe L. B. Evaluating the varied appearances of normal and abnormal varrow. MRI Web Clinic - December 2010. www. protopracs. com 10. Shah L.M., Hanrahan C. MRI of spinal bone marrov: Part I, techniques and normal age-related appearances / AJR.- 2011. V.197. P. 1298 1308.

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